You need to be careful running too much advance, it can cause serious problem. (like melted pistons, etc) I'd say european spec is probably fine, since chances are the us spec is retarted for emissions reasons. Not sure about anything over .95-1.0 though. If you get too advanced it becomes counterproductive because you're injecting too early. There is an optimum.
For anyone who's really serious about tuning, I'd suggest getting a pyrometer to watch your exhaust gas temps because that gives you a pretty good idea what's going on in there and gives you some warning if it's running too hot.
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